The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal.
第一作者:
H L,Grimes
第一单位:
Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.
作者:
主题词
3T3细胞(3T3 Cells);氨基酸序列(Amino Acid Sequence);动物(Animals);碱基序列(Base Sequence);细胞周期(Cell Cycle);细胞转化, 肿瘤(Cell Transformation, Neoplastic);鸡(Chickens);氯霉素O-乙酰转移酶(Chloramphenicol O-Acetyltransferase);共有序列(Consensus Sequence);DNA结合蛋白质类(DNA-Binding Proteins);果蝇属(Drosophila);G1期(G1 Phase);基因, 报告(Genes, Reporter);人类(Humans);白细胞介素2(Interleukin-2);小鼠(Mice);分子序列数据(Molecular Sequence Data);诱变, 定点(Mutagenesis, Site-Directed);原癌基因(Proto-Oncogenes);大鼠(Rats);重组蛋白质类(Recombinant Proteins);阻遏蛋白质类(Repressor Proteins);逆转录病毒科(Retroviridae);序列同源性, 氨基酸(Sequence Homology, Amino Acid);螺(Snails);胸腺瘤(Thymoma);胸腺肿瘤(Thymus Neoplasms);转录因子(Transcription Factors);转染(Transfection);脊椎动物(Vertebrates);爪蟾属(Xenopus);锌指(Zinc Fingers)
DOI
10.1128/MCB.16.11.6263
PMID
8887656
发布时间
2022-03-21
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