Comparative modelling and analysis of amino acid substitutions suggests that the family of pregnancy-associated glycoproteins includes both active and inactive aspartic proteinases.
第一作者:
K,Guruprasad
第一单位:
Department of Crystallography, Birkbeck College, University of London, UK.
作者:
医学主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);结合部位(Binding Sites);牛(Cattle);马(Horses);氢键合(Hydrogen Bonding);分子序列数据(Molecular Sequence Data);寡肽类(Oligopeptides);胃酶抑素类(Pepstatins);肽碎片(Peptide Fragments);种系发生(Phylogeny);妊娠蛋白质类(Pregnancy Proteins);蛋白酶抑制药(Protease Inhibitors);蛋白质结合(Protein Binding);蛋白质结构, 三级(Protein Structure, Tertiary);序列比对(Sequence Alignment);绵羊(Sheep);猪(Swine)
DOI
10.1093/protein/9.10.849
PMID
8931124
发布时间
2019-09-09
基金项目
HD 29483/HD/NICHD NIH HHS/United States
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Protein engineering
849-56页
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