Introduction of a glycosylation site into a secreted protein provides evidence for an alternative antigen processing pathway: transport of precursors of major histocompatibility complex class I-restricted peptides from the endoplasmic reticulum to the cytosol.
第一作者:
I,Bacik
第一单位:
Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892-0440, USA.
作者:
主题词
动物(Animals);抗原呈递(Antigen Presentation);生物转运(Biological Transport);胞质溶胶(Cytosol);内质网(Endoplasmic Reticulum);糖基化(Glycosylation);组织相容性抗原Ⅰ类(Histocompatibility Antigens Class I);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 近交CBA(Mice, Inbred CBA);核壳蛋白质类(Nucleocapsid Proteins);核蛋白类(Nucleoproteins);肽碎片(Peptide Fragments);RNA结合蛋白质类(RNA-Binding Proteins);病毒核心蛋白质类(Viral Core Proteins)
DOI
10.1084/jem.186.4.479
PMID
9254646
发布时间
2024-09-22
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