Limited efficacy of the HSV-TK/GCV system for gene therapy of malignant gliomas and perspectives for the combined transduction of the interleukin-4 gene.
第一作者:
S,Benedetti
第一单位:
Istituto Nazionale Neurologico C. Besta, Department of Biochemistry and Genetics, Milano, Italy.
作者:
主题词
动物(Animals);抗代谢药(Antimetabolites);女(雌)性(Female);更昔洛韦(Ganciclovir);基因转移技术(Gene Transfer Techniques);遗传载体(Genetic Vectors);神经胶质瘤(Glioma);白细胞介素4(Interleukin-4);小鼠(Mice);小鼠, 裸(Mice, Nude);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);逆转录病毒科(Retroviridae);单纯疱疹病毒属(Simplexvirus);胸苷激酶(Thymidine Kinase);转导, 遗传(Transduction, Genetic);病毒蛋白质类(Viral Proteins)
DOI
10.1089/hum.1997.8.11-1345
PMID
9295129
发布时间
2013-11-21
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Human gene therapy
1345-53页
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