The tax protein of human T-cell leukemia virus type 1 mediates the transactivation of the c-sis/platelet-derived growth factor-B promoter through interactions with the zinc finger transcription factors Sp1 and NGFI-A/Egr-1.
第一作者:
S R,Trejo
第一单位:
Division of Molecular Oncology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
作者:
医学主题词
碱基序列(Base Sequence);结合部位(Binding Sites);共有序列(Consensus Sequence);DNA结合蛋白质类(DNA-Binding Proteins);早期生长反应蛋白质1(Early Growth Response Protein 1);基因产物, tax(Gene Products, tax);基因, 报告(Genes, Reporter);人类嗜T淋巴细胞病毒1型(Human T-lymphotropic virus 1);人类(Humans);即早蛋白质类(Immediate-Early Proteins);萤光素酶类(Luciferases);寡脱氧核糖核苷酸类(Oligodeoxyribonucleotides);血小板源性生长因子(Platelet-Derived Growth Factor);启动区, 遗传(Promoter Regions, Genetic);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质c-sis(Proto-Oncogene Proteins c-sis);重组融合蛋白质类(Recombinant Fusion Proteins);Sp1转录因子(Sp1 Transcription Factor);T淋巴细胞(T-Lymphocytes);模板, 遗传(Templates, Genetic);转录因子(Transcription Factors);转录, 遗传(Transcription, Genetic);转录激活(Transcriptional Activation);转染(Transfection);肿瘤细胞, 培养的(Tumor Cells, Cultured);锌指(Zinc Fingers)
DOI
10.1074/jbc.272.43.27411
PMID
9341193
发布时间
2021-12-03
基金项目
5 T32 HL07088/HL/NHLBI NIH HHS/United States
CA63417/CA/NCI NIH HHS/United States
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