The X-linked immunodeficiency defect in the mouse is corrected by expression of human Bruton's tyrosine kinase from a yeast artificial chromosome transgene.
第一作者:
A,Maas
第一单位:
Department of Cell Biology and Genetics, Faculty of Medicine, Erasmus University Rotterdam, The Netherlands.
作者:
医学主题词
动物(Animals);抗体生成(Antibody Formation);抗原, T细胞非依赖性(Antigens, T-Independent);B-淋巴细胞(B-Lymphocytes);染色体, 人工, 酵母(Chromosomes, Artificial, Yeast);女(雌)性(Female);遗传互补测验(Genetic Complementation Test);人类(Humans);免疫缺陷综合征(Immunologic Deficiency Syndromes);男(雄)性(Male);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases)
DOI
10.1002/eji.1830270910
PMID
9341757
发布时间
2018-12-01
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