FGF signaling activates STAT1 and p21 and inhibits the estrogen response and proliferation of MCF-7 cells.
第一作者:
M R,Johnson
第一单位:
Department of Microbiology and the Kaplan Cancer Center, New York University School of Medicine, NY 10016, USA.
作者:
医学主题词
乳腺肿瘤(Breast Neoplasms);钙-钙调素依赖性蛋白激酶类(Calcium-Calmodulin-Dependent Protein Kinases);细胞分裂(Cell Division);周期素依赖激酶抑制剂p21(Cyclin-Dependent Kinase Inhibitor p21);细胞周期蛋白类(Cyclins);DNA结合蛋白质类(DNA-Binding Proteins);减量调节(Down-Regulation);酶抑制剂(Enzyme Inhibitors);雌激素类(Estrogens);成纤维细胞生长因子(Fibroblast Growth Factors);基因表达调控(Gene Expression Regulation);人类(Humans);肿瘤, 激素依赖性(Neoplasms, Hormone-Dependent);受体, 成纤维细胞生长因子(Receptors, Fibroblast Growth Factor);STAT1转录因子(STAT1 Transcription Factor);信号传导(Signal Transduction);反式激活因子类(Trans-Activators);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1038/sj.onc.1201789
PMID
9632141
发布时间
2007-11-15
- 浏览21
Oncogene
2647-56页
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