DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.
第一作者:
S,Kasibhatla
第一单位:
Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, San Diego, California 92121, USA.
作者:
医学主题词
抗原, 表面(Antigens, Surface);细胞凋亡(Apoptosis);钙-钙调素依赖性蛋白激酶类(Calcium-Calmodulin-Dependent Protein Kinases);DNA损伤(DNA Damage);Fas配体蛋白质(Fas Ligand Protein);基因表达调控, 酶学(Gene Expression Regulation, Enzymologic);人类(Humans);JNK丝裂原活化蛋白激酶类(JNK Mitogen-Activated Protein Kinases);Jurkat细胞(Jurkat Cells);膜糖蛋白类(Membrane Glycoproteins);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);分子序列数据(Molecular Sequence Data);NF-κB(NF-kappa B);启动区, 遗传(Promoter Regions, Genetic);信号传导(Signal Transduction);T淋巴细胞(T-Lymphocytes);转录因子AP-1(Transcription Factor AP-1)
DOI
10.1016/s1097-2765(00)80054-4
PMID
9660938
发布时间
2019-09-14
基金项目
CA 69831/CA/NCI NIH HHS/United States
GM 52735/GM/NIGMS NIH HHS/United States
- 浏览9
Molecular cell
543-51页
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