A sequence within the cytoplasmic tail of GpIIb independently activates platelet aggregation and thromboxane synthesis.
第一作者:
G,Stephens
第一单位:
Centre for Cardiovascular Science, Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin 2, Ireland.
作者:
医学主题词
乙酸盐类(Acetates);细胞系(Cell Line);双特异性磷酸酶2(Dual Specificity Phosphatase 2);脂肪酸类, 不饱和(Fatty Acids, Unsaturated);流式细胞术(Flow Cytometry);人类(Humans);肼类(Hydrazines);整合素类(Integrins);显微镜检查, 荧光(Microscopy, Fluorescence);肽碎片(Peptide Fragments);血小板活化(Platelet Activation);血小板聚集(Platelet Aggregation);血小板聚集抑制剂(Platelet Aggregation Inhibitors);血小板糖蛋白GPⅡb-Ⅲa复合物(Platelet Glycoprotein GPIIb-IIIa Complex);蛋白质磷酸酶2(Protein Phosphatase 2);蛋白质酪氨酸磷酸酶类(Protein Tyrosine Phosphatases);信号传导(Signal Transduction);血栓烷A2(Thromboxane A2);酪氨酸(Tyrosine)
DOI
10.1074/jbc.273.32.20317
PMID
9685382
发布时间
2021-02-09
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