Polymorphisms in the dihydrofolate reductase (DHFR) and dihydropteroate synthetase (DHPS) genes of Plasmodium falciparum and in vivo resistance to sulphadoxine/pyrimethamine in isolates from Tanzania.
第一作者:
T,Jelinek
第一单位:
London School of Hygiene and Tropical Medicine, Department of Medical Parasitology, UK. jelinek@lrz.uni-muenchen.de
作者:
医学主题词
动物(Animals);抗疟药(Antimalarials);儿童(Child);儿童, 学龄前(Child, Preschool);DNA引物(DNA Primers);二氢蝶酸合酶(Dihydropteroate Synthase);抗药性, 微生物(Drug Resistance, Microbial);女(雌)性(Female);人类(Humans);婴儿(Infant);疟疾, 恶性(Malaria, Falciparum);男(雄)性(Male);恶性疟原虫(Plasmodium falciparum);聚合酶链反应(Polymerase Chain Reaction);乙胺嘧啶(Pyrimethamine);磺胺多辛(Sulfadoxine);坦桑尼亚(Tanzania);四氢叶酸脱氢酶(Tetrahydrofolate Dehydrogenase)
DOI
10.1046/j.1365-3156.1998.00280.x
PMID
9735930
发布时间
2019-09-21
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