换一批
换一批Synthesis and tyrosine kinase inhibitory activity of a series of 2-amino-8H-pyrido[2,3-d]pyrimidines: identification of potent, selective platelet-derived growth factor receptor tyrosine kinase inhibitors.
作者：
主题词
3T3细胞(3T3 Cells);动物(Animals);生物利用度(Biological Availability);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);酶抑制剂(Enzyme Inhibitors);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 裸(Mice, Nude);肌, 平滑, 血管(Muscle, Smooth, Vascular);磷酰化(Phosphorylation);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);吡啶酮类(Pyridones);嘧啶类(Pyrimidines);大鼠(Rats);大鼠, Wistar(Rats, Wistar);受体, 成纤维细胞生长因子(Receptors, Fibroblast Growth Factor);受体, 血小板源生长因子(Receptors, Platelet-Derived Growth Factor);构效关系(Structure-Activity Relationship);移植, 异种(Transplantation, Heterologous);肿瘤细胞, 培养的(Tumor Cells, Cultured);src族激酶类(src-Family Kinases)
DOI
10.1021/jm980398y
PMID
9784112
发布时间
2019-12-10
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