Role of folic acid in modulating the toxicity and efficacy of the multitargeted antifolate, LY231514.
第一作者:
J F,Worzalla
第一单位:
Cancer Research Division, Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, IN 46285, USA.
作者:
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞分裂(Cell Division);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);酶抑制剂(Enzyme Inhibitors);女(雌)性(Female);叶酸(Folic Acid);叶酸缺乏(Folic Acid Deficiency);谷氨酸盐类(Glutamates);鸟嘌呤(Guanine);人类(Humans);半数致死量(Lethal Dose 50);白血病L5178(Leukemia L5178);小鼠(Mice);小鼠, 近交DBA(Mice, Inbred DBA);小鼠, 裸(Mice, Nude);胸苷酸合酶(Thymidylate Synthase);肿瘤细胞, 培养的(Tumor Cells, Cultured)
PMID
9858888
发布时间
2015-11-19
- 浏览4
Anticancer research
3235-9页
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