换一批
换一批Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice.
第一作者：
M W,Holladay
第一单位：
Neurological and Urological Diseases Research, Abbott Laboratories, Abbott Park, IL 60064-3500, USA.
作者：
主题词
生物碱类(Alkaloids);镇痛药, 非麻醉(Analgesics, Non-Narcotic);动物(Animals);吖丁啶类(Azetidines);吖辛因类(Azocines);结合部位(Binding Sites);脑(Brain);小鼠(Mice);烟碱激动剂(Nicotinic Agonists);疼痛测定(Pain Measurement);吡啶类(Pyridines);喹嗪类(Quinolizines);大鼠(Rats);受体, 烟碱(Receptors, Nicotinic);立体异构现象(Stereoisomerism);构效关系(Structure-Activity Relationship);氚(Tritium)
DOI
10.1016/s0960-894x(98)00504-6
PMID
9873625
发布时间
2019-08-19
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