换一批A leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand-receptor complexes to lysosomes.
第一作者：
S J,Kil
第一单位：
Department of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106-4970, USA.
作者：
医学主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);COS细胞(COS Cells);细胞区室化(Cell Compartmentation);细胞系(Cell Line);细胞质(Cytoplasm);狗(Dogs);胞吞作用(Endocytosis);表皮生长因子(Epidermal Growth Factor);己糖胺酶类(Hexosaminidases);人类(Humans);亮氨酸(Leucine);配体(Ligands);溶酶体(Lysosomes);分子序列数据(Molecular Sequence Data);诱变, 定点(Mutagenesis, Site-Directed);构效关系(Structure-Activity Relationship)
DOI
10.1074/jbc.274.5.3141
PMID
9915853
发布时间
2021-02-09
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