A misleading false-negative result of Pneumocystis real-time PCR assay due to a rare punctual mutation: A French multicenter study

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作者： Le Gal, Solene ^[1] ; Robert-Gangneux, Florence ^[2] ; Pepino, Yann ^[3] ; Belaz, Sorya ^[4] ; Damiani, Celine ^[5] ; Gueguen, Paul ^[6] ; Pitous, Melanie ^[7] ; Virmaux, Michele ^[8] ; Lissillour, Eloise ^[9] ; Pougnet, Laurence ^[10] ; Guillaud-Saumur, Thibaud ; Toubas, Dominique ; Valot, Stephane ; Hennequin, Christophe ; Morio, Florent ; Hasseine, Lilia ; Bouchara, Jean-Philippe ; Totet, Anne ; Nevez, Gilles

作者单位： Univ Brest, GEIHP EA 3142, Brest, France ^[1] Brest Univ Hosp, Lab Mol Genet & Histocompatibil, Brest, France ^[2] Nantes Univ Hosp, Parasitol & Mycol Lab, Nantes, France ^[3] Univ Rennes 1, INSERM U1085, Rennes, France ^[4] Nice Univ Hosp, Parasitol & Mycol Lab, Nice, France ^[5] Dijon Univ Hosp, Parasitol & Mycol Lab, Dijon, France ^[6] Univ Picardy Jules Verne, EA UMR I INERIS 4285 01, Amiens, France ^[7] Reims Univ Hosp, Parasitol & Mycol Lab, Reims, France ^[8] St Antoine Hosp, AP HP, Parasitol & Mycol Lab, Paris, France ^[9] Univ Angers, GEIHP EA 3142, Angers, France ^[10]

关键词 Real time-PCR Pneumocystis jirovecii PCP mutation TaqMan (R) MGB probe

发布时间 2017-09-22

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