Novel chimeric porcine circovirus (PCV) with the capsid gene of the emerging PCV2b subtype cloned in the genomic backbone of the non-pathogenic PCV1 is attenuated in vivo and induces protective and cross-protective immunity against PCV2b and PCV2a subtypes in pigs

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作者： Beach, Nathan M. ^[1] ; Ramamoorthy, Sheela ^[2] ; Opriessnig, Tanja ^[3] ; Wu, Stephen Q. ^[4] ; Meng, Xiang-Jin .

作者单位： Virginia Polytech Inst and State Univ, Dept Biomed Sci and Pathobiol, Coll Vet Med, CRC Integrated Life Sci Bldg,1981 Kraft Dr, Blacksburg, VA 24061 USA ^[1] Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States ^[2] Fort Dodge Animal Health, Inc., Fort Dodge, IA, United States ^[3] Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, United States ^[4]

关键词 porcine circovirus type1-2 chimeric viral vaccine: immunologic-drug immunostimulant-drug vaccine protective immunity genome viral load cross-protective immunity lymphoid lesion

发布时间 2013-11-20

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