首页>Bioorganic and Medicinal Chemistry Letters>Use of structure based design to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A (PDE10A) inhibitors against phosphodiesterase 3 (PDE3)
Use of structure based design to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A (PDE10A) inhibitors against phosphodiesterase 3 (PDE3)
作者单位：Department of Pharmacokinetics and Drug Metabolism, Amgen Inc., One Amgen Center Drive, Thousand[1]Department of Small Molecule Chemistry, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320[2]Department of Neuroscience, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320-1799[3]Department of Molecular Structure and Characterizations, Amgen Inc., One Amgen Center Drive[4]
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