Oleanolic acid methyl ester, a novel cytotoxic mitocan, induces cell cycle arrest and ROS-Mediated cell death in castration-resistant prostate cancer PC-3 cells

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作者： Noha Abdelmageed ^[1] ; Samy A.F. Morad ^[2] ; Ashraf A. Elghoneimy ^[3] ; Tatiana Syrovets ^[4] ; Thomas Simmet ^[5] ; Hesham El-zorba ^[6] ; Hossney A. El-Banna ; Myles Cabot ; Magdy I. Abdel-Aziz

作者单位： Department of Biochemistry and Molecular Biology, East Carolina University, Brody School of ^[1] Department of Pharmacology, College of Vet. Med. (Kafr El-Sheikh) Tanta University ^[2] Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University ^[3] Department of Pharmacology, Faculty of Veterinary Medicine, South Valley University ^[4] Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University ^[5] Department of Pharmacology, Faculty of Veterinary Medicine, Sohag University ^[6]

关键词 Triterpenoids Oleanolic acid Mitocan ROS Apoptosis Cell cycle arrest Mitochondrial apoptotic pathway

发布时间 2018-11-10

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Biomedicine & pharmacotherapy =

2017年96卷

417-425页

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Oleanolic acid methyl ester, a novel cytotoxic mitocan, induces cell cycle arrest and ROS-Mediated cell death in castration-resistant prostate cancer PC-3 cells

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Oleanolic acid methyl ester, a novel cytotoxic mitocan, induces cell cycle arrest and ROS-Mediated cell death in castration-resistant prostate cancer PC-3 cells

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