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Spheroid glioblastoma culture conditions as antigen source for dendritic cell-based immunotherapy: spheroid proteins are survival-relevant targets but can impair immunogenic interferon gamma production

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第一作者： Erhart, Friedrich

作者： Erhart, Friedrich ^[1] ; Weiss, Tamara ^[2] ; Klingenbrunner, Simone ^[2] ; Fischhuber, Katrin ^[2] ; Reitermaier, Rene ^[3] ; Halfmann, Angela ^[3] ; Blauensteiner, Bernadette ^[1] ; Loetsch, Daniela ^[4] ; Spiegl-Kreinecker, Sabine ^[5] ; Berger, Walter ^[6] ; Sialana, Fernando J. ^[2] ; Lubec, Gert ^[6] ; Felzmann, Thomas ^[7] ; Dohnal, Alexander ^[6] ; Visus, Carmen ^[2]

作者单位： Univ Vienna, Fac Life Sci, Dept Pharmaceut Chem, Div Drug Design & Med Chem, Vienna, Austria ^[1] Activartis Biotech GmbH, Vienna, Austria ^[2] Med Univ Vienna, Ctr Comprehens Canc, Inst Canc Res, Vienna, Austria ^[3] St Anna Kinderkrebsforsch Childrens Canc Res Inst, Dept Tumor Biol, Vienna, Austria ^[4] Johannes Kepler Univ Linz, Kepler Univ Hosp, Univ Clin Neurosurg, Linz, Austria ^[5] St Anna Kinderkrebsforsch Childrens Canc Res Inst, Dept Tumor Immunol, Zimmermannpl 10, A-1090 Vienna, Austria ^[6] Med Univ Vienna, Dept Neurosurg, Vienna, Austria ^[7]

关键词 antigen source dendritic cell glioblastoma immunogenicity immunotherapy quantitative proteomics spheroid culture conditions

发布时间 2019-12-08

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