An integrative in silico system for predicting dysregulated genes in the human epileptic focus: Application to SLC transporters

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作者： Mirza, Nasir ^[1] ; Vasieva, Olga ^[2] ; Appleton, Richard ^[3] ; Burn, Sasha ^[4] ; Carr, Daniel ^[5] ; Crooks, Daniel ^[6] ; du Plessis, Daniel ^[7] ; Duncan, Roderick ^[8] ; Farah, Jibril Osman ^[9] ; Josan, Vivek ^[10] ; Miyajima, Fabio ; Mohanraj, Rajiv ; Shukralla, Arif ; Sills, Graeme J. ; Marson, Anthony G. ; Pirmohamed, Munir

作者单位： Walton Ctr NHS Fdn Trust, Dept Neuropathol, Liverpool, Merseyside, England ^[1] Alder Hey Childrens NHS Fdn Trust, Paediat Neurosci Fdn, Roald Dahl EEG Unit, Liverpool, Merseyside ^[2] Univ Liverpool, Inst Integrat Biol, Liverpool, Merseyside, England ^[3] Univ Liverpool, Dept Mol & Clin Pharmacol, Block A Waterhouse Bldg,1-5 Brownlow St, Liverpool L69 ^[4] Alder Hey Childrens NHS Fdn Trust, Dept Neurosurg, Liverpool, Merseyside, England ^[5] Christchurch Hosp, Dept Neurol, Christchurch, New Zealand ^[6] Walton Ctr NHS Fdn Trust, Dept Neurosurg, Liverpool, Merseyside, England ^[7] Salford Royal NHS Fdn Trust, Dept Cellular Pathol, Salford, Lancs, England ^[8] Salford Royal NHS Fdn Trust, Dept Neurol, Salford, Lancs, England ^[9] Salford Royal NHS Fdn Trust, Dept Neurosurg, Salford, Lancs, England ^[10]

关键词 Computational gene prioritization Convergent functional genomics Hippocampal sclerosis Epilepsy Solute carrier transporters Microarray Pharmacoresistance

发布时间 2017-04-06

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