Berberine induces apoptosis in glioblastoma multiforme U87MG cells via oxidative stress and independent of AMPK activity

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作者： Palma, Tais Vidal ^[1] ; Lenz, Luana Sueling ^[2] ; Bottari, Nathiele Bianchin ^[3] ; Pereira, Aline ^[3] ; Schetinger, Maria Rosa Chitolina ^[4] ; Morsch, Vera Maria ^[4] ; Ulrich, Henning ^[4] ; Pillat, Micheli Mainardi ^[4] ; de Andrade, Cinthia Melazzo ^[5]

作者单位： Fed Univ Santa Maria RS, Dept Small Anim Clin, Ctr Rural Sci, Room 121,Vet Hosp Bldg,Ave Roraima 1000, Santa Maria 97105900, RS, Brazil ^[1] Univ Fed Santa Maria, Dept Microbiol & Parasitol, Hlth Sci Ctr, Santa Maria, RS, Brazil ^[2] Univ Fed Santa Maria, Biochem & Oxidat Stress Sect Therapy Lab Cellular, Postgrad Program Biol Sci Biochem Toxicol, Santa Maria, RS, Brazil ^[3] Univ Fed Santa Maria, Dept Chem, Postgrad Program Biol Sci Biochem Toxicol, Ctr Nat & Exact Sci, Santa Maria, RS, Brazil ^[4] Univ Sao Paulo, Inst Chem, Dept Biochem, Sao Paulo, SP, Brazil ^[5]

关键词 Glioma Apoptosis Oxidative stress Phytotherapy ROS AMPK

发布时间 2020-12-27

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