A drug-resistant beta-lactamase variant changes the conformation of its active-site proton shuttle to alter substrate specificity and inhibitor potency-论文-万方医学网

A drug-resistant beta-lactamase variant changes the conformation of its active-site proton shuttle to alter substrate specificity and inhibitor potency

导出原文传递

翻译打印收藏纠错

作者： Soeung, Victoria ^[1] ; Lu, Shuo ^[2] ; Hu, Liya ^[3] ; Judge, Allison ; Sankaran, Banumathi ; Prasad, B. V. Venkataram ; Palzkill, Timothy

作者单位： Dept Biochem & Mol Biol,Baylor Coll Med ^[1] Dept Pharmacol & Chem Biol,Baylor Coll Med ^[2] Berkeley Ctr Struct Biol,Lawrence Berkeley Natl Lab ^[3]

关键词 beta-lactamase antibiotics antibiotic resistance enzyme inhibitor enzyme structure enzyme kinetics DEPENDENT ROTAMER LIBRARY CLASS-A STAPHYLOCOCCUS-AUREUS ANTIBIOTIC-RESISTANCE ACYLATION MECHANISM MOLECULAR-BASIS 3 DECADES HYDROLYSIS INSIGHTS CEPHALOSPORINS

发布时间 2022-05-28

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交

浏览0

相似文献

中文期刊
外文期刊
学位论文
会议论文

检索历史清除

A drug-resistant beta-lactamase variant changes the conformation of its active-site proton shuttle to alter substrate specificity and inhibitor potency

相似文献

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

A drug-resistant beta-lactamase variant changes the conformation of its active-site proton shuttle to alter substrate specificity and inhibitor potency

相似文献

相关期刊

检索历史清除