Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
第一作者:
Arking,D.E.
作者:
Arking,D.E. [1]
;
Pulit,S.L. [2]
;
Crotti,L. [3]
;
VanDerHarst,P. [4]
;
Munroe,P.B. [5]
;
Koopmann,T.T. [6]
;
Sotoodehnia,N. [7]
;
Rossin,E.J. [8]
;
Morley,M. [9]
;
Wang,X. [10]
;
Johnson,A.D. [11]
;
Lundby,A. [12]
;
Gudbjartsson,D.F. [13]
;
Noseworthy,P.A. [14]
;
Eijgelsheim,M. [15]
;
Bradford,Y. [16]
;
Tarasov,K.V. [17]
;
D?rr,M. [18]
;
Müller-Nurasyid,M. [19]
;
Lahtinen,A.M. [20]
;
Nolte,I.M. [21]
;
Smith,A.V. [22]
;
Bis,J.C. [23]
;
Isaacs,A. [24]
;
Newhouse,S.J. [25]
;
Evans,D.S. [26]
;
Post,W.S. [27]
;
Waggott,D. [28]
;
Lyytik?inen,L.-P. [29]
;
Hicks,A.A. [30]
;
Eisele,L. [31]
;
Ellinghaus,D. [32]
;
Hayward,C. [33]
;
Navarro,P. [34]
;
Ulivi,S. [35]
;
Tanaka,T. [36]
;
Tester,D.J. [37]
;
Chatel,S. [38]
;
Gustafsson,S. [39]
;
Kumari,M. [40]
;
Morris,R.W. [41]
;
Naluai,A.T. [42]
;
Padmanabhan,S. [43]
;
Kluttig,A. [44]
;
Strohmer,B. [45]
;
Panayiotou,A.G. [46]
;
Torres,M. [47]
;
Knoflach,M. [48]
;
Hubacek,J.A. [49]
;
Slowikowski,K. [50]
;
Raychaudhuri,S. [51]
;
Kumar,R.D. [52]
;
Harris,T.B. [53]
;
Launer,L.J. [54]
;
Shuldiner,A.R. [55]
;
Alonso,A. [56]
;
Bader,J.S. [57]
;
Ehret,G. [58]
;
Huang,H. [59]
;
Kao,W.H.L. [60]
;
Strait,J.B. [61]
;
Macfarlane,P.W. [62]
;
Brown,M. [63]
;
Caulfield,M.J. [64]
;
Samani,N.J. [65]
;
Kronenberg,F. [66]
;
Willeit,J. [67]
;
Smith,J.G. [68]
;
Greiser,K.H. [69]
;
ZuSchwabedissen,H.M. [70]
;
Werdan,K. [71]
;
Carella,M. [72]
;
Zelante,L. [73]
;
Heckbert,S.R. [74]
;
Psaty,B.M. [75]
;
Rotter,J.I. [76]
;
Kolcic,I. [77]
;
Pola?ek,O. [78]
;
Wright,A.F. [79]
;
Griffin,M. [80]
;
Daly,M.J. [81]
;
Arnar,D.O. [82]
;
Hólm,H. [83]
;
Thorsteinsdottir,U. [84]
;
Denny,J.C. ;
Roden,D.M. ;
Zuvich,R.L. ;
Emilsson,V. ;
Plump,A.S. ;
Larson,M.G. ;
O'Donnell,C.J. ;
Yin,X. ;
Bobbo,M. ;
D'Adamo,A.P. ;
Iorio,A. ;
Sinagra,G. ;
Carracedo,A. ;
Cummings,S.R. ;
Nalls,M.A. ;
Jula,A. ;
Kontula,K.K. ;
Marjamaa,A. ;
Oikarinen,L. ;
Perola,M. ;
Porthan,K. ;
Erbel,R. ;
Hoffmann,P. ;
J?ckel,K.-H. ;
K?lsch,H. ;
N?then,M.M. ;
DenHoed,M. ;
Loos,R.J.F. ;
Thelle,D.S. ;
Gieger,C. ;
Meitinger,T. ;
Perz,S. ;
Peters,A. ;
Prucha,H. ;
Sinner,M.F. ;
Waldenberger,M. ;
DeBoer,R.A. ;
Franke,L. ;
VanDerVleuten,P.A. ;
Beckmann,B.M. ;
Martens,E. ;
Bardai,A. ;
Hofman,N. ;
Wilde,A.A.M.
作者单位:
Department of Pediatrics, Division of Pediatric Cardiology, Mayo Clinic, Rochester, MN, United
[1]
Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health
[2]
Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech
[3]
Department of Medicine, University of Maryland, School of Medicine, Baltimore, MD, United States
[4]
Heart Failure Research Center, Department of Clinical and Experimental Cardiology, Academic Medical
[5]
Electrocardiology, University of Glasgow Institute of Cardiovascular and Medical Sciences, Royal
[6]
Chronic Disease Epidemiology and Prevention Unit, National Institute for Health and Welfare
[7]
Institute of Genetic Epidemiology, Helmholtz Zentrum Munich-German Research Center for
[8]
Department of Medicine I, University Hospital Munich, Ludwig Maximilians Universit?t, Munich
[9]
Medical Genetics Unit, Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
[10]
Department of Cardiovascular Science, University of Leicester, Glenfield Hospital, Leicester
[11]
Broad Institute of MIT and Harvard, Cambridge, MA, United States, Computer Science and Artificial
[12]
Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam
[13]
Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia
[14]
Institute of Cardiovascular Science, University College London, London, United Kingdom
[15]
Computational and Systems Biology Program, Division of Biology and Biomedical Sciences, Washington
[16]
Informatics and Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, ON, Canada
[17]
Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala
[18]
BHF Glasgow Cardiovascular Research Centre, College of Medical, Veterinary and Life Sciences
[19]
Vascular Screening and Diagnostic Centre, London, United Kingdom
[20]
Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany, Institute of
[21]
Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
[22]
Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany
[23]
Institute for Maternal and Child Health, Burlo Garofolo Trieste, Trieste, Italy, Clinical
[24]
Research Programs Unit, Molecular Medicine, University of Helsinki, Helsinki, Finland, Department
[25]
Christine Kühne-Center for Allergy and Education, Munich, Germany, Department of Dermatology and
[26]
Department of Clinical Genetics, Academic Medical Center, Amsterdam, Netherlands
[27]
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States
[28]
Department of Medicine III, Medical Faculty, Martin Luther University Halle-Wittenberg, Halle
[29]
Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy
[30]
Department of Pharmacology, Ernst Moritz Arndt University of Greifswald, Greifswald, Germany
[31]
Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen
[32]
Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, MD
[33]
DZHK (German Centre for Cardiovascular Research), Partner site Munich Heart Alliance, Munich
[34]
Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen
[35]
Department of Medicine, University of Helsinki, Helsinki, Finland
[36]
Laboratory of Cardiovascular Sciences, Human Cardiovascular Studies Unit, National Institute on
[37]
Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, United States
[38]
Department of Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands
[39]
Department of Clinical Chemistry, Fimlab Laboratories and University of Tampere, School of Medicine
[40]
Institute for Medical Informatics,Biometry and Epidemiology, University Hospital of Essen
[41]
Institute for Maternal and Child Health, Burlo Garofolo Trieste, Trieste, Italy
[42]
Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, United States
[43]
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
[44]
Cyprus International Institute for Environmental and Public Health in association, Harvard School
[45]
Medical Research Council (MRC) Human Genetics Unit, Institute of Genetics and Molecular Medicine
[46]
Center for Complex Disease Genomics, Johns Hopkins University, School of Medicine, Baltimore, MD
[47]
Icelandic Heart Association, Kopavogur, Iceland, Faculty of Medicine, University of Iceland
[48]
Institut du Thorax, Centre Hospitalier Universitaire de Nantes, Université de Nantes, Nantes
[49]
Cardiovascular Department, Ospedali Riuniti and University of Trieste, Trieste, Italy
[50]
Department of Medical and Clinical Genetics, Sahlgrenska Academy, University of Gothenburg
[51]
Department of Primary Care and Population Health, University College London, Royal Free Campus
[52]
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota
[53]
Department of Biomedical Informatics, Vanderbilt University, School of Medicine, Nashville, TN
[54]
Department of Medicine, Division of Cardiology, Helsinki University Central Hospital, Helsinki
[55]
Institute for Biological and Medical Imaging, Helmholtz Zentrum München-German Research Center for
[56]
California Pacific Medical Center Research Institute, San Francisco, CA, United States
[57]
Grupo de Medicina Xenómica, Centro de Investigación Biomédica en Red de Enfermedades Raras
[58]
Clinical Pharmacology, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
[59]
Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland
[60]
Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA
[61]
Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany, DZHK
[62]
Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
[63]
MRC Epidemiology Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom
[64]
Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore
[65]
Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research
[66]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA
[67]
Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States
[68]
Center for Human Genetics Research, Vanderbilt University, School of Medicine, Nashville, TN
[69]
Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen
[70]
Clinical Pharmacology, Barts and the London School of Medicine, Queen Mary University of London
[71]
Sanofi Research and Development, Paris, France
[72]
Division of Cardiology, Johns Hopkins University, School of Medicine, Baltimore, MD, United States
[73]
Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United
[74]
Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for
[75]
Division of Genetic Epidemiology, Innsbruck Medical University, Innsbruck, Austria
[76]
Department of Medicine, Division of Cardiology, Landspitali University Hospital, Reykjavik, Iceland
[77]
Institute of Medical Epidemiology,Biostatistics and Informatics, Martin Luther University Halle
[78]
Icelandic Heart Association, Kopavogur, Iceland
[79]
Department of Molecular Medicine, Section of Cardiology, University of Pavia, Pavia, Italy, Center
[80]
Second Department of Internal Medicine, Paracelsus Medical University/Salzburger Landeskliniken
[81]
Department of Cardiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany
[82]
Department of Medicine, Vanderbilt University, School of Medicine, Nashville, TN, United States
[83]
National Heart,Lung,and Blood Institute (NHLBI) Framingham Heart Study, Framingham, MA, United
[84]
发布时间
2016-04-19
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Nature Genetics
Nature Genetics
826-836页
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