Structurally simple, potent, Plasmodium selective farnesyltransferase inhibitors that arrest the growth of malaria parasites

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作者： Glenn MP ^[1] ; Chang SY ^[2] ; Horney C ^[3] ; Rivas K ^[4] ; Yokoyama K ^[5] ; Pusateri EE ^[6] ; Fletcher S ^[7] ; Cummings CG ^[8] ; Buckner FS ; Pendyala PR

作者单位： Univ Washington, Dept Biochem, Seattle, WA 98195 USA ^[1] Univ Washington, Dept Chem & Biochem, Seattle, WA 98195 USA ^[2] Univ Washington, Dept Med, Seattle, WA 98195 USA ^[3] ahosp.com ^[4] Univ S Florida, Dept Oncol, H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL 33612 USA ^[5] Yale Univ, Dept Chem, New Haven, CT 06511 USA ^[6] Univ S Florida, Dept Biochem & Mol Biol, H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL 33612 USA ^[7] Univ Cent Florida, Dept Mol Biol & Microbiol, Orlando, FL 32826 USA ^[8]

关键词 PROTEIN FARNESYLTRANSFERASE ANTIMALARIAL-DRUGS FALCIPARUM DISCOVERY FARNESYL CELLS

发布时间 2013-11-20

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