Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model

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作者： Dassie,E. ^[1] ; Andrews,M.R. ^[2] ; Bensadoun,J.-C. ^[3] ; Cacquevel,M. ^[4] ; Schneider,B.L. ; Aebischer,P. ; Wouters,F.S. ; Richardson,J.C. ; Hussain,I. ; Howlett,D.R. ; Spillantini,M.G. ; Fawcett,J.W.

作者单位： Neurodegenerative Studies Laboratory, Brain Mind Institute, école Polytechnique Fédérale de ^[1] GlaxoSmithKline, R and D China U.K. Group, Stevenage, United Kingdom ^[2] Laboratory for Molecular and Cellular Systems, Department of Neurophysiology and Sensory Physiology ^[3] Department of Clinical Neurosciences, Cambridge University Centre for Brain Repair, Cambridge ^[4]

关键词 Adeno-associated virus Alzheimer's disease Alzheimer's precursor protein Memory Neurodegeneration Tau Tauopathy Viral vectors

发布时间 2013-11-20

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