Tryptophan 46 is a site for ethanol and ivermectin action in P2X4 receptors

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作者： Maya Popova ^[1] ; James Trudell ^[2] ; Kaixun Li ; Ronald Alkana ; Daryl Davies ; Liana Asatryan

作者单位： Alcohol and Brain Research Laboratories, Titus Family Department of Clinical Pharmacy & Pharmaceutical Economics and Policy, School of Pharmacy, University of Southern California, 1985 Zonal Avenue, Los Angeles, CA 90089, USA ^[1] Department of Anesthesia and Beckman Program for Molecular and Genetic Medicine, Stanford School of Medicine, Stanford, CA 94305, USA ^[2]

关键词 ATP-gated P2X4 receptors Ethanol and ivermectin sensitivity Site-directed mutagenesis Xenopus oocytes Whole-cell two-electrode voltage clamp Position 46 GluCl Molecular model Homology model Zebrafish

发布时间 2014-11-14

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