A novel murine model for contact lens wear reveals clandestine IL-1R dependent corneal parainflammation and susceptibility to microbial keratitis upon inoculation with Pseudomonas aeruginosa

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作者： Metruccio, Matteo M. E. ^[1] ; Wan, Stephanie J. ^[2] ; Horneman, Hart ^[3] ; Kroken, Abby R. ^[4] ; Sullivan, Aaron B. ; Truong, Tan N. ; Mun, James J. ; Tam, Connie K. P. ; Frith, Robin ; Welsh, Laurence ; George, Melanie D. ; Morris, Carol A. ; Evans, David J. ; Fleiszig, Suzanne M. J.

作者单位： Univ Calif Berkeley, Sch Optometry, Berkeley, CA 94720 USA ^[1] CooperVis UK R&D Facil, Eastleigh SO534LY, Hants, England ^[2] CooperVision Inc, Adv Dev Ctr, Pleasanton, CA 94588 USA ^[3] Univ Calif Berkeley, Grad Grp Vis Sci, Berkeley, CA 94720 USA ^[4]

关键词 Murine contact lens Parainflammation IL-1R CD11c-positive cells Ly6G-positive cells Neutrophils Pseudomonas aeruginosa keratitis

发布时间 2019-10-15

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