Neuroprotectant androst-3 beta, 5 alpha, 6 beta-triol suppresses TNF-alpha-induced endothelial adhesion molecules expression and neutrophil adhesion to endothelial cells by attenuation of CYLD-NF-kappa B pathway

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作者： Yan, Min ^[1] ; Leng, Tiandong ^[2] ; Tang, Lipeng ^[3] ; Zheng, Xiaoke ^[4] ; Lu, Bingzheng ^[5] ; Li, Yuan ^[6] ; Sheng, Longxiang ; Lin, Suizhen ; Shi, Haitao ; Yan, Guangmei ; Yin, Wei

作者单位： Sun Yat Sen Univ, Zhongshan Sch Med, Dept Biochem, Guangzhou 510080, Guangdong, Peoples R China ^[1] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Pathol, Guangzhou 510080, Guangdong, Peoples R China ^[2] Guangdong Provinces Tradit Chinese Med Hosp, Dept Pharmacol Tradit Chinese Med, Guangzhou 510120 ^[3] Sun Yat Sen Univ, Zhongshan Sch Med, Dept Pharmacol, Guangzhou 510080, Guangdong, Peoples R China ^[4] Morehouse Sch Med, Neurosci Inst, Atlanta, GA 30310 USA ^[5] Guangzhou Cellprotek Pharmaceut, G Bldg F-4,3 Lanyue Rd, Guangzhou 510663, Guangdong, Peoples R ^[6]

关键词 Androst-3 beta 5 alpha 6 beta-triol Adhesion molecules Leukocyte adhesion Brain microvascular endothelial cells NF-kappa B activation CYLD

发布时间 2019-09-05

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