Physiological adaptations affecting drug pharmacokinetics in space: what do we really know? A critical review of the literature-论文-万方医学网

Physiological adaptations affecting drug pharmacokinetics in space: what do we really know? A critical review of the literature

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作者： Cinzia Dello Russo ^[1] ; Tiziano Bandiera ^[2] ; Monica Monici ^[3] ; Leonardo Surdo ^[4] ; Vincent Lai Ming Yip ^[5] ; Virginia Wotring ^[6] ; Lucia Morbidelli ^[7]

作者单位： Department of Healthcare Surveillance and Bioethics, Section of Pharmacology,Università Cattolica ^[1] D3‐PharmaChemistry Line,Istituto Italiano di Tecnologia (IIT) ^[2] ASAcampus Joint Laboratory, ASA Res. Div. & Dept. of Experimental and Clinical Biomedical Sciences ^[3] Space Applications Services NV/SA for the European Space Agency ^[4] MRC Centre for Drug Safety Science and Wolfson Centre for Personalised Medicine, Institute of ^[5] International Space University ^[6] Department of Life Sciences,University of Siena ^[7]

关键词 animal studies bed rest studies therapeutic drugs drug formulation pharmacokinetics pharmacotherapy in space real evidence in space space stressor

发布时间 2022-07-13

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