The PI3K alpha inhibitor DFX24 suppresses tumor growth and metastasis in non-small cell lung cancer via ERK inhibition and EPHB6 reactivation-论文-万方医学网

The PI3K alpha inhibitor DFX24 suppresses tumor growth and metastasis in non-small cell lung cancer via ERK inhibition and EPHB6 reactivation

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作者： Fan, Yan-Hua ^[1] ; Ding, Huai-Wei ^[2] ; Kim, Donghwa ^[3] ; Liu, Jian-Yu ; Hong, Ji-Young ; Xu, Yong-Nan ; Wang, Daoping ; Yang, Xiao-Sheng ; Lee, Sang Kook

作者单位： Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550014, Peoples R China ^[1] Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang ^[2] Seoul Natl Univ, Nat Prod Res Inst, Coll Pharm, Seoul 08826, South Korea ^[3]

关键词 PI3K alpha inhibitor EPHB6 quinazolin-4(3H)-one analog(DFX24)Cell cycle arrest Apoptosis Non-Small cell lung cancer (NSCLC)

发布时间 2022-09-11

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