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Codon stabilization analysis of the "248" temperature sensitive mutation for increased phenotypic stability of respiratory syncytial virus vaccine candidates.

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第一作者： Luongo, C.

作者： Luongo, C. ^[1] ; Yang, L. J. ; Winter, C. C. ; Spann, K. M. ; Murphy, B. R. ; Collins, P. L. ; Buchholz, U. J.

作者单位： Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892-8007, USA ^[1]

关键词 amino acids animal models attenuation candidate vaccines codons genetic stability glutamine in vitro laboratory animals leucine mutations phenotypes phenylalanine temperature viral diseases Human respiratory syncytial virus mice

发布时间 2013-11-20

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2009年27卷41期

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2009年27卷41期

5667-5676页

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Codon stabilization analysis of the "248" temperature sensitive mutation for increased phenotypic stability of respiratory syncytial virus vaccine candidates.

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Codon stabilization analysis of the "248" temperature sensitive mutation for increased phenotypic stability of respiratory syncytial virus vaccine candidates.

Vaccine

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