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Secretory phospholipase A2-IIA and cardiovascular disease: A mendelian randomization study

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作者: Holmes,M.V. [1] ; Simon,T. [2] ; Exeter,H.J. [3] ; Folkersen,L. [4] ; Asselbergs,F.W. [5] ; Guardiola,M. [6] ; Cooper,J.A. [7] ; Palmen,J. [8] ; Hubacek,J.A. [9] ; Carruthers,K.F. [10] ; Horne,B.D. [11] ; Brunisholz,K.D. [12] ; Mega,J.L. [13] ; VanIperen,E.P.A. [14] ; Li,M. [15] ; Leusink,M. [16] ; Trompet,S. [17] ; Verschuren,J.J.W. [18] ; Hovingh,G.K. [19] ; Dehghan,A. [20] ; Nelson,C.P. [21] ; Kotti,S. [22] ; Danchin,N. [23] ; Scholz,M. [24] ; Haase,C.L. [25] ; Rothenbacher,D. [26] ; Swerdlow,D.I. [27] ; Kuchenbaecker,K.B. [28] ; Staines-Urias,E. [29] ; Goel,A. [30] ; Van'THooft,F. [31] ; Gertow,K. [32] ; DeFaire,U. [33] ; Panayiotou,A.G. [34] ; Tremoli,E. [35] ; Baldassarre,D. [36] ; Veglia,F. [37] ; Holdt,L.M. [38] ; Beutner,F. [39] ; Gansevoort,R.T. [40] ; Navis,G.J. [41] ; MateoLeach,I. [42] ; Breitling,L.P. [43] ; Brenner,H. [44] ; Thiery,J. [45] ; Dallmeier,D. [46] ; Franco-Cereceda,A. [47] ; Boer,J.M.A. [48] ; Stephens,J.W. [49] ; Hofker,M.H. [50] ; Tedgui,A. [51] ; Hofman,A. [52] ; Uitterlinden,A.G. [53] ; Adamkova,V. [54] ; Pitha,J. [55] ; Onland-Moret,N.C. [56] ; Cramer,M.J. [57] ; Nathoe,H.M. [58] ; Spiering,W. [59] ; Klungel,O.H. [60] ; Kumari,M. [61] ; Whincup,P.H. [62] ; Morrow,D.A. [63] ; Braund,P.S. [64] ; Hall,A.S. ; Olsson,A.G. ; Doevendans,P.A. ; Trip,M.D. ; Tobin,M.D. ; Hamsten,A. ; Watkins,H. ; Koenig,W. ; Nicolaides,A.N. ; Teupser,D. ; Day,I.N.M. ; Carlquist,J.F. ; Gaunt,T.R. ; Ford,I. ; Sattar,N. ; Tsimikas,S. ; Schwartz,G.G. ; Lawlor,D.A. ; Morris,R.W. ; Sandhu,M.S. ; Poledne,R. ; Maitland-VanDerZee,A.H. ; Khaw,K.-T. ; Keating,B.J. ; VanDerHarst,P. ; Price,J.F. ; Mehta,S.R. ; Yusuf,S. ; Witteman,J.C.M. ; Franco,O.H. ; Jukema,J.W. ; DeKnijff,P. ; Tybjaerg-Hansen,A. ; Rader,D.J. ; Farrall,M. ; Samani,N.J. ; Kivimaki,M. ; Fox,K.A.A. ; Humphries,S.E. ; Anderson,J.L. ; Boekholdt,S.M. ; Palmer,T.M. ; Eriksson,P. ; Paré,G. ; Hingorani,A.D. ; Sabatine,M.S. ; Mallat,Z. ; Casas,J.P. ; Talmud,P.J.
作者单位: Division of Cardiovascular Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge [1] Stockholm Heart Center Stockholm, Link?ping University, Linkoping, Sweden [2] Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech [3] Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht [4] Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, Netherlands [5] Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet [6] Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London [7] Assistance Publique-H?pitaux de Paris (AP-HP), H?pital Saint-Antoine, Department of Clinical [8] Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands [9] University Medical Center Groningen, University of Groningen, Department of Cardiology, Groningen [10] Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands, Department of [11] Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands, Interuniversity [12] Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United Kingdom [13] Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, UT, United States [14] Department of Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands, Netherlands Consortium [15] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Department [16] Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom [17] MRC Centre for Causal Analyses in Translational Epidemiology (CAiTE), School of Social and [18] Unitat de Recerca en Lípids i Arteriosclerosi, IISPV, Universitat Rovira i Virgili, Reus, Spain [19] Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet [20] Diabetes Research Group, Institute of Life Sciences, Swansea University, Swansea, United Kingdom [21] Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom [22] Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom [23] University Medical Center Groningen, University of Groningen, Department of Internal Medicine [24] Dipartimento di Scienze Farmacologiche e Biomolecolari, Universitá di Milano, Milan, Italy, Centro [25] Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam [26] Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom [27] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of [28] Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine [29] LIFE: Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany [30] Departments of Health Sciences and Genetics, University of Leicester, Leicester, United Kingdom [31] Centre for Population Health Sciences, University of Edinburgh, United Kingdom [32] Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton [33] Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm [34] Netherlands Consortium on Healthy Aging (NCHA), Leiden, Netherlands, Department of Internal [35] Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom [36] Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada [37] Department of Primary Care and Population Health, University College London, Royal Free Campus [38] Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Netherlands [39] Divison of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston [40] Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands [41] British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow [42] Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, United States [43] Division of Cardiovascular Diseases, Department of Medicine, University of California San Diego [44] Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center [45] Assistance Publique H?pitaux de Paris, H?pital Européen Georges Pompidou, Department of Cardiology [46] Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical [47] Department for Nutrition and Health, National Institute for Public Health and the Environment [48] Inserm U970, Paris-Cardiovascular Research Center, Paris, France [49] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg [50] Division of Population Health Sciences and Education, St George's University of London, London [51] Department of Vascular Surgery, Imperial College, London, United Kingdom [52] Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, Ulm, Germany [53] Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen [54] Department of Epidemiology and Public Health, Faculty of Population Health Sciences, University [55] Centro Cardiologico Monzino, IRCCS, Milan, Italy [56] Department of Pathology and Medical Biology, University of Groningen, University Medical Center [57] VA Medical Center and University, Colorado School of Medicine, Denver, CO, United States [58] Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands [59] Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine [60] Cyprus Cardiovascular Educational and Research Trust, Nicosia, Cyprus [61] Preventive Cardiovascular Medicine, Penn Heart and Vascular Center, Philadelphia, PA, United States [62] Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig [63] Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany, Division of Clinical [64]
发布时间 2014-05-18
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Journal of the American College of Cardiology

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