Production of 2-Hydroxyglutarate by IDH Mutant Malignancies Induces a BRCAness State That Can be Exploited By PARP Inhibitors and Radiation

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作者： Corso, C. D. ^[1] ; Bindra, R. S. ^[2] ; Glazer, P. M. ^[3] ; Sulkowski, P. L. ^[4] ; Robinson, N. D. ; Scanlon, S. E. ; Purshouse, K. R. ; Bai, H. ; Liu, Y. ; Sundaram, R. K. ; Hegan, D. C. ; Fons, N. R. ; Breuer, G. A. ; Song, Y. ; Mishra-Gorur, K. ; De Feyter, H. M. ; de Graaf, R. A. ; Surovtseva, Y. V. ; Kachman, M. ; Halene, S. ; Gunel, M.

作者单位： Univ Michigan, Sch Med, Ann Arbor, MI USA ^[1] Yale Univ, Sch Med, Dept Therapeut Radiol, New Haven, CT 06510 USA ^[2] Yale Univ, Sch Med, New Haven, CT USA ^[3] Yale Ctr Mol Discovery, West Haven, CT USA ^[4]

发布时间 2020-08-12

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International Journal of Radiation Oncology, Biology, Physics

2017年99卷2S期

E68-E68页

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Production of 2-Hydroxyglutarate by IDH Mutant Malignancies Induces a BRCAness State That Can be Exploited By PARP Inhibitors and Radiation

International Journal of Radiation Oncology, Biology, Physics

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International Journal of Radiation Oncology, Biology, Physics

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Production of 2-Hydroxyglutarate by IDH Mutant Malignancies Induces a BRCAness State That Can be Exploited By PARP Inhibitors and Radiation

International Journal of Radiation Oncology, Biology, Physics

相似文献

International Journal of Radiation Oncology, Biology, Physics

相关期刊

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