Differential responses to JNJ-37822681, a specific and fast dissociating dopamine D2 receptor antagonist, in cynomolgus monkey and Sprague-Dawley rat general toxicology studies: clinical observations, prolactin levels, mammary histopathology findings and toxicokinetics

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作者： de Waal, Eric J. ^[1] ; Desmidt, Maria ^[2] ; Korte, Sven ^[3] ; Niehoff, Marc ; Chase, Kevan ; Arrowsmith, Wayne ; Lampo, Ann

作者单位： Covance Labs GmbH, Munster, Germany ^[1] Huntingdon Res Ctr, Huntingdon Life Sci, Huntingdon PE28 4HS, Cambs, England ^[2] Janssen Res & Dev, Drug Safety Sci, Dept Preclin Project Dev, B-2340 Beerse, Belgium ^[3]

关键词 JNJ-37822681 antipsychotic dopamine D-2 receptor antagonist extrapyramidal symptoms EPS prolactin monkey rat

发布时间 2019-11-13

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Journal of applied toxicology

2014年34卷9/10期

974-992页

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Differential responses to JNJ-37822681, a specific and fast dissociating dopamine D2 receptor antagonist, in cynomolgus monkey and Sprague-Dawley rat general toxicology studies: clinical observations, prolactin levels, mammary histopathology findings and toxicokinetics

Journal of applied toxicology

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Journal of applied toxicology

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Differential responses to JNJ-37822681, a specific and fast dissociating dopamine D2 receptor antagonist, in cynomolgus monkey and Sprague-Dawley rat general toxicology studies: clinical observations, prolactin levels, mammary histopathology findings and toxicokinetics

Journal of applied toxicology

相似文献

Journal of applied toxicology

相关期刊

检索历史清除