Methionine excess in diet induces acute lethal hepatitis in mice lacking cystathionine γ-lyase, an animal model of cystathioninuria

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作者： Yamada,H. ^[1] ; Akahoshi,N. ^[2] ; Kamata,S. ^[3] ; Hagiya,Y. ^[4] ; Hishiki,T. ^[5] ; Nagahata,Y. ^[6] ; Matsuura,T. ^[7] ; Takano,N. ; Mori,M. ; Ishizaki,Y. ; Izumi,T. ; Kumagai,Y. ; Kasahara,T. ; Suematsu,M. ; Ishii,I.

作者单位： Suematsu Gas Biology Project, Exploratory Research for Advanced Technology, Japan Science and ^[1] Department of Molecular and Cellular Neurobiology, Graduate School of Medicine, Gunma University ^[2] Department of Biochemistry, School of Medicine, Keio University, Tokyo 160-8582, Japan, Department ^[3] Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo 105 ^[4] Department of Biochemistry, School of Medicine, Keio University, Tokyo 160-8582, Japan, Suematsu ^[5] Environmental Medicine Section, Graduate School of Comprehensive Human Sciences, University of ^[6] Department of Biochemistry, School of Medicine, Keio University, Tokyo 160-8582, Japan ^[7]

关键词 Antioxidants Homocysteine Metabolome Methionine sulfoxide Transamination Transsulfuration

发布时间 2013-11-20

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