Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation

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作者： Kangawa, Yumi ^[1] ; Yoshida, Toshinori ^[2] ; Maruyama, Kiyoshi ^[3] ; Okamoto, Minako ^[4] ; Kihara, Tohru ; Nakamura, Michi ; Ochiai, Masako ; Hippo, Yoshitaka ; Hayashi, Shim-mo ; Shibutani, Makoto

作者单位： Tokyo Univ Agr & Technol, Lab Vet Pathol, 3-5-8 Saiwai Cho, Fuchu, Tokyo 1838509, Japan ^[1] Natl Canc Ctr, Dept Anim Experimentat, Fundamental Innovat Oncol Core Ctr, 5-1-1 Tsukiji, Tokyo ^[2] Kaken Pharmaceut Co Ltd, Pharmacokinet & Safety Res Dept, Drug Res Ctr, 301 Gensuke, Fujieda ^[3] San Ei Gen FFI Inc, Global Sci & Regulatory Affairs, 1-1-11 Sanwa Cho, Toyonaka, Osaka 5618588 ^[4]

关键词 Cilostazol Enzymatically modified isoquercitrin Reactive oxygen species Colorectal cancer Murine azoxymethane/dextran sodium sulphate-induced colorectal carcinoma model

发布时间 2017-10-13

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