A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia

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作者： Odenike, Olatoyosi ^[1] ; Halpern, Anna ^[2] ; Godley, Lucy A. ^[3] ; Madzo, Jozef ^[4] ; Karrison, Theodore ; Green, Margaret ; Fulton, Noreen ; Mattison, Ryan J. ; Yee, Karen W. L. ; Bennett, Meghan ; Koval, Gregory ; Malnassy, Gregory ; Larson, Richard A. ; Ratain, Mark J. ; Stock, Wendy

作者单位： Univ Chicago, Dept Med, Chicago, IL 60637 USA ^[1] Univ Wisconsin, Madison, WI USA ^[2] Princess Margaret Hosp, Toronto, ON M4X 1K9, Canada ^[3] Univ Chicago Comprehens Canc Ctr, Chicago, IL USA ^[4]

关键词 Belinostat Azacitidine Myeloid neoplasm Histone deacetylase inhibitor DNA methyltransferase inhibitor MDR1 DNA hypomethylating agent

发布时间 2015-07-18

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