The effect of sustained virological response by direct-acting antivirals on insulin resistance and diabetes mellitus in patients with chronic hepatitis C
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DAAschronic hepatitis Cinsulin resistancetype 2 diabetes mellitusChronic hepatitis C virus (HCV) infection affects 1-2 of the world population and is a primary cause of liver morbidity and mortality including liver cirrhosis and hepatocellular carcinoma. FurthermoreHCV is directly or indirectly involved in HCV-associated extrahepatic manifestations such as lympho-proliferative processesautoimmune conditionsand cardiovascularrenaland nervous system diseasesInsulin resistance (IR) is a feature of HCV infection reported up to 70 of cases and is involved in changes in glucose metabolism and in the development of type 2 diabetes mellitus (T2DM) that is observed with a higher prevalence in patients with HCV infected compared to non-infected subjects [1]IR and T2DM negatively affect b
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2020-09-23
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