Phase 1 study of mTORC1/2 inhibitor sapanisertib (TAK-228) in advanced solid tumours, with an expansion phase in renal, endometrial or bladder cancer
作者:
Voss, Martin H. [1]
;
Gordon, Michael S. [2]
;
Mita, Monica [3]
;
Rini, Brian [4]
;
Makker, Vicky [5]
;
Macarulla, Teresa [6]
;
Smith, David C. [7]
;
Cervantes, Andres [8]
;
Puzanov, Igor [9]
;
Pili, Roberto [10]
;
Wang, Ding [11]
;
Jalal, Shadia [12]
;
Pant, Shubham [13]
;
Patel, Manish R. [14]
;
Neuwirth, Rachel L. [15]
;
Enke, Aaron [16]
;
Shou, Yaping ;
Sedarati, Farhad ;
Faller, Douglas V. ;
Burris, Howard A., III
作者单位:
Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Dept Hematol & Oncol, 8700 Beverly Blvd
[1]
Cleveland Clin Fdn, Dept Solid Tumor Oncol, 9500 Euclid Ave, Cleveland, OH 44195 USA
[2]
Mem Sloan Kettering Canc Ctr, Dept Med, 300 East 66th St, New York, NY 10065 USA
[3]
Vall dHebron Univ Hosp, Dept Med Oncol, Passeig Vall dHebron,119,129, Barcelona 08035, Spain
[4]
Univ Michigan, Dept Internal Med, 1500 E Med Ctr Dr, Ann Arbor, MI 48109 USA
[5]
Univ Valencia, Biomed Res Inst INCLIVA, Dept Med Oncol, CIBERONC, Avda Menendez Pelayo 4 Acc
[6]
Vanderbilt Univ, Div Hematol Oncol, Dept Med, Med Ctr, 1161 21st Ave S, Nashville, TN 37232 USA
[7]
Indiana Univ, Div Hematol Oncol, Dept Med, Simon Canc Ctr, 535 Barnhill Dr, Indianapolis, IN 46202
[8]
Henry Ford Hlth Syst, Hematol Oncol, 1 Ford Pl, Detroit, MI 48202 USA
[9]
Indiana Univ, Hematol Oncol, Melvin & Bren Simon Canc Ctr, 535 Barnhill Dr, Indianapolis, IN 46202
[10]
Univ Texas MD Anderson Canc Ctr, Dept Invest Canc Therapeut, 1515 Holcombe Blvd, Houston, TX 77030
[11]
Florida Canc Specialists SCRI, Drug Dev Unit, 600 N Cattlemen Rd 200, Sarasota, FL 34232 USA
[12]
Millennium Pharmaceut Inc, Biostat, 40 Landsdowne St, Cambridge, MA 02139 USA
[13]
Millennium Pharmaceut Inc, Oncol Clin Res, 40 Landsdowne St, Cambridge, MA 02139 USA
[14]
Sarah Cannon Res Inst Tennessee Oncol, Drug Dev Unit, 250 25th Ave, North Nashville, TN 37203 USA
[15]
HonorHlth Res Inst, Oncol Res, 10510 N 92nd St Suite 200, Scottsdale, AZ 85258 USA
[16]
发布时间
2022-09-11
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