From Ergolines to Indoles: Improved Inhibitors of the Human H3 Receptor for the Treatment of Narcolepsy

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作者： Auberson, Yves P. ^[1] ; Troxler, Thomas ^[1] ; Zhang, Xuechun ^[2] ; Yang, Charles R. ^[2] ; Feuerbach, Dominik ^[1] ; Liu, Yu-Chih ^[3] ; Lagu, Bharat ^[1] ; Perrone, Mark ^[3] ; Lei, Lijun ^[3] ; Shen, Xiaoxia ^[1] ; Zhang, Dushan ^[1] ; Wang, Chunxiu ^[3] ; Wang, Tie-Lin ^[1] ; Briner, Karin ^[2] ; Bock, Mark G. ^[1]

作者单位： ChemPartner, Pudong New Area, Shanghai 201203, Peoples R China ^[1] Novartis Pharma AG, Novartis Inst BioMed Res, CH-4058 Basel, Switzerland ^[2] Novartis Inst BioMedical Res Inc, Cambridge, MA 02139 USA ^[3]

关键词 H3 receptor histamine indoles medicinal chemistry neurotransmitters

发布时间 2015-07-31

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