AT-527, a Double Prodrug of a Guanosine Nucleotide Analog, Is a Potent Inhibitor of SARS-CoV-2 In Vitro and a Promising Oral Antiviral for Treatment of COVID-19-论文-万方医学网

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AT-527, a Double Prodrug of a Guanosine Nucleotide Analog, Is a Potent Inhibitor of SARS-CoV-2 In Vitro and a Promising Oral Antiviral for Treatment of COVID-19

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第一作者： Good, Steven S.

作者： Good, Steven S. ^[1] ; Westover, Jonna ^[2] ; Jung, Kie Hoon ^[3] ; Zhou, Xiao-Jian ^[4] ; Moussa, Adel ; La Colla, Paolo ; Collu, Gabriella ; Canard, Bruno ; Sommadossi, Jean-Pierre

作者单位： Atea Pharmaceut Inc, Boston, MA 02110 USA ^[1] Utah State Univ, Dept Anim Dairy & Vet Sci, Logan, UT 84322 USA ^[2] Univ Cagliari, Monserrato, Italy ^[3] Architecture & Fonct Macromol Biol, Marseille, France ^[4]

关键词 AT-527 AT-511 AT-9010 COVID-19 SARS-CoV-2 triphosphate lung

发布时间 2022-09-11

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AT-527, a Double Prodrug of a Guanosine Nucleotide Analog, Is a Potent Inhibitor of SARS-CoV-2 In Vitro and a Promising Oral Antiviral for Treatment of COVID-19

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AT-527, a Double Prodrug of a Guanosine Nucleotide Analog, Is a Potent Inhibitor of SARS-CoV-2 In Vitro and a Promising Oral Antiviral for Treatment of COVID-19

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