Discovery and evaluation of Atopaxar hydrobromide, a novel JAK1 and JAK2 inhibitor, selectively induces apoptosis of cancer cells with constitutively activated STAT3-论文-万方医学网

Discovery and evaluation of Atopaxar hydrobromide, a novel JAK1 and JAK2 inhibitor, selectively induces apoptosis of cancer cells with constitutively activated STAT3

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作者： Sun, Jingjie ^[1] ; Du, Yuping ^[2] ; Zhang, Xinxin ; Wan, Zhuoya ; Lin, Yuxi ; Song, Qiaoling ; Wang, Xiao ; Guo, Jihui ; Li, Shanshan ; Nan, Jing ; Yang, Jinbo

作者单位： Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Gansu, Peoples R China ^[1] Qingdao Natl Lab Marine Sci & Technol, Innovat Ctr Marine Drug Screening & Evaluat, Qingdao 266100 ^[2]

关键词 JAK1 JAK2 STAT3 Chemical inhibitor Atopaxar hydrobromide Cancer

发布时间 2022-10-11

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Discovery and evaluation of Atopaxar hydrobromide, a novel JAK1 and JAK2 inhibitor, selectively induces apoptosis of cancer cells with constitutively activated STAT3

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Discovery and evaluation of Atopaxar hydrobromide, a novel JAK1 and JAK2 inhibitor, selectively induces apoptosis of cancer cells with constitutively activated STAT3

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