At Critically Low Antigen Densities, IgM Hexamers Outcompete Both IgM Pentamers and IgG1 for Human Complement Deposition and Complement-Dependent Cytotoxicity-论文-万方医学网

At Critically Low Antigen Densities, IgM Hexamers Outcompete Both IgM Pentamers and IgG1 for Human Complement Deposition and Complement-Dependent Cytotoxicity

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作者： Oskam, Nienke ^[1] ; Ooijevaar-de Heer, Pleuni ^[2] ; Derksen, Ninotska I. L. ^[3] ; Kruithof, Simone ; de Taeye, Steven W. ; Vidarsson, Gestur ; Reijm, Sanne ; Kissel, Theresa ; Toes, Rene E. M. ; Rispens, Theo

作者单位： Sanquin Res,Acad Med Ctr ^[1] Landsteiner Lab,Acad Med Ctr ^[2] Med Ctr,Leiden Univ ^[3]

关键词 IMMUNOGLOBULIN-M J-CHAIN MONOCLONAL-ANTIBODIES CELL-SURFACE ACTIVATION C1Q REQUIREMENTS RECOGNITION SECRETION COMPONENT

发布时间 2022-09-16

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At Critically Low Antigen Densities, IgM Hexamers Outcompete Both IgM Pentamers and IgG1 for Human Complement Deposition and Complement-Dependent Cytotoxicity

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At Critically Low Antigen Densities, IgM Hexamers Outcompete Both IgM Pentamers and IgG1 for Human Complement Deposition and Complement-Dependent Cytotoxicity

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