The PU.1 and NF-EM5 binding motifs in the Igkappa 3' enhancer are responsible for directing somatic hypermutations to the intrinsic hotspots in the transgenic Vkappa gene.

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作者： Kodama M ^[1] ; Hayashi R ^[2] ; Nishizumi H ; Nagawa F ; Takemori T ; Sakano H

作者单位： Department of Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. ^[1] anaceum.am.lublin.pl ^[2]

关键词 B-Lymphocytes Genes Immunoglobulin Immunoglobulins kappa-Chain Somatic Hypermutation B淋巴细胞基因免疫球蛋白免疫球蛋白类 κ链

发布时间 2013-11-20

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International immunology

2001年13卷11期

1415-1422页

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The PU.1 and NF-EM5 binding motifs in the Igkappa 3' enhancer are responsible for directing somatic hypermutations to the intrinsic hotspots in the transgenic Vkappa gene.

International immunology

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International immunology

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The PU.1 and NF-EM5 binding motifs in the Igkappa 3' enhancer are responsible for directing somatic hypermutations to the intrinsic hotspots in the transgenic Vkappa gene.

International immunology

相似文献

International immunology

相关期刊

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