Safety, tolerability and pharmacokinetics and pharmacodynamics of HL2351, a novel hybrid fc‐fused interleukin‐1 receptor antagonist, in healthy subjects: A first‐in‐human study

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作者： Oh Jaeseong ^[1] ; Huh Ki Young ^[2] ; Cho Young‐Gyu ^[3] ; Cha Ji‐Eun ^[4] ; Kim Se‐Jin ^[5] ; Yoon Seo Hyun ; Park Sung Sup ; Yoon Hyunyee ; Lee Jieon ; Lee Howard

作者单位： Y BiologicsDaejeon,Republic of Korea ^[1] HANDOK Inc.Seoul,Republic of Korea ^[2] Department of Laboratory MedicineSeoul National University College of Medicine and HospitalSeoul ^[3] Protein Immunology Core Facility, Biomedical Research InstitutesSeoul National University ^[4] Department of Clinical Pharmacology and TherapeuticsSeoul National University College of Medicine ^[5]

关键词 biopharmaceutics monoclonal antibodies pharmacodynamics pharmacokinetics

发布时间 2020-06-03

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