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Rationally Designed, Conformationally Constrained Inverse Agonists of ROR gamma t-Identification of a Potent, Selective Series with Biologic-Like in Vivo Efficacy

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第一作者： Marcoux, David

作者： Marcoux, David ^[1] ; Duan, James J. -W. ^[2] ; Shi, Qing ; Cherney, Robert J. ; Srivastava, Anurag S. ; Cornelius, Lyndon ; Batt, Douglas G. ; Liu, Qingjie ; Beaudoin-Bertrand, Myra ; Weigelt, Carolyn A. ; Khandelwal, Purnima ; Vishwakrishnan, Sureshbabu ; Selvakumar, Kumaravel ; Karmakar, Ananta ; Gupta, Arun Kumar ; Basha, Mushkin ; Ramlingam, Sridharan ; Manjunath, Naveen ; Vanteru, Sridhar ; Karmakar, Sukhen ; Maddala, Nageswara ; Vetrichelvan, Muthalagu ; Gupta, Anuradha ; Rainpulla, Richard A. ; Mathur, Arvind ; Yip, Shiuhang ; Li, Peng ; Wu, Dauh-Rurng ; Khan, Javed ; Ruzanov, Max ; Sack, John S. ; Wang, Jinhong ; Yarde, Melissa ; Cvijic, Mary Ellen ; Li, Sha ; Shuster, David J. ; Borowski, Virna ; Xie, Jenny H. ; McIntyre, Kim W. ; Obermeier, Mary T. ; Fura, Aberra ; Stefanski, Kevin ; Cornelius, Georgia ; Hynes, John, Jr. ; Tino, Joseph A. ; Macor, John E. ; Salter-Cid, Luisa ; Denton, Rex ; Zhao, Qihong ; Carter, Percy H. ; Dhare, T. G. Murali

作者单位： Biocon Bristol Myers Squibb Res Ctr, Dept Discovery Synth, Biocon Pk,Bommasandra 4 Phase,Jigani Link Rd, Bengaluru 560099, India ^[1] Bristol Myers Squibb, Res & Dev, 3551 Lawrenceville Rd, Princeton, NJ 08540 USA ^[2]

发布时间 2021-09-04

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