Synthesis and evaluation of 1-(substituted)-3-prop-2-ynylureas as antiangiogenic agents

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作者： Sanphanya,K. ^[1] ; Wattanapitayakul,S.K. ^[2] ; Prangsaengtong,O. ^[3] ; Jo,M. ^[4] ; Koizumi,K. ^[5] ; Shibahara,N. ; Priprem,A. ; Fokin,V.V. ; Vajragupta,O.

作者单位： Department of Chemistry, Scripps Research Institute, 10550 North Torrey Pines Rd., San Diego, CA ^[1] Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayudya Rd ^[2] Department of Pharmacology, Faculty of Medicine, Srinakharinwirot University, 114 Sukhumvit 23 ^[3] Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Khon Kaen University ^[4] Department of Kampo Diagnostics, Institute of Natural Medicine, University of Toyama, 2630 Sugitani ^[5]

关键词 1-(Substituted)-3-prop-2-ynylurea Antiangiogenic agent Cytotoxic agents EGFR kinase inhibitor Tyrosine kinase inhibitors

发布时间 2013-11-20

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