Disruption of insulin receptor substrate-2 impairs growth but not insulin function in rats-论文-万方医学网

Disruption of insulin receptor substrate-2 impairs growth but not insulin function in rats

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作者： Toyoshima, Yuka ^[1] ; Nakamura, Katsuyuki ^[2] ; Tokita, Reiko ^[3] ; Teramoto, Naomi ; Sugihara, Hidetoshi ; Kato, Hisanori ; Yamanouchi, Keitaro ; Minami, Shiro

作者单位： Nippon Med Sch,Nippon Med Sch, Inst Adv Med Sci, Dept Bioregulat, Nakahara Ku, Kosugi Machi ^[1] Univ Tokyo,Univ Tokyo, Grad Sch Agr & Life Sci, Dept Vet Physiol, Bunkyo Ku, Tokyo, Japan ^[2] Univ Tokyo,Univ Tokyo, Grad Sch Agr & Life Sci, Dept Appl Biol Chem, Bunkyo Ku, Tokyo, Japan ^[3]

关键词 insulin insulin-like growth factor insulin receptor substrate-2 growth glucose metabolism CRISPR Cas phosphorylation insulin-like growth factor (IGF)IRS PROTEINS SERINE PHOSPHORYLATION PLECKSTRIN HOMOLOGY OXIDATIVE STRESS BETA-CELLS RESISTANCE GLUCOSE MICE MUTATIONS DOMAINS

发布时间 2022-05-28

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