Continuous infusion of physostigmine in patients with perioperative septic shock: A pharmacokinetic/pharmacodynamic study with population pharmacokinetic modeling

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作者： Pinder, Nadine ^[1] ; Zimmermann, Johannes B. ^[2] ; Gastine, Silke ^[3] ; Wuerthwein, Gudrun ^[4] ; Hempel, Georg ; Bruckner, Thomas ; Hoppe-Tichy, Torsten ; Weigand, Markus A. ; Swoboda, Stefanie

作者单位： Heidelberg Univ Hosp, IMBI, Tower West,Neuenheimer Feld 130-3, D-69120 Heidelberg, Germany ^[1] Heidelberg Univ Hosp, Pharm Dept, Neuenheimer Feld 670, D-69120 Heidelberg, Germany ^[2] Heidelberg Univ Hosp, Dept Anesthesiol, Neuenheimer Feld 110, D-69120 Heidelberg, Germany ^[3] Univ Munster, Dept Pharmaceut & Med Chem Clin Pharm, Corrensstr 48, D-48149 Munster, Germany ^[4]

关键词 Anticholium Cholinergic anti-inflammatory pathway Cholinesterase inhibitor Critically ill patients Physostigmine salicylate Steady state concentration

发布时间 2020-02-12

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