A prodrug of epigallocatechin-3-gallate alleviates high glucose-induced proangiogenic factor production by inhibiting the ROS/TXNIP/NLRP3 inflammasome axis in retinal Muller cells

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作者： Du, Jingxia ^[1] ; Wang, Ying ^[2] ; Tu, Yuanyuan ^[3] ; Guo, Yang ^[4] ; Sun, Xiaodong ; Xu, Xun ; Liu, Xiaojuan ; Wang, Li ; Qin, Xiao ; Zhu, Manhui ; Song, E.

作者单位： Soochow Univ, Affiliated Hosp 2, Dept Ophthalmol, Suzhou, Jiangsu, Peoples R China ^[1] Soochow Univ, Lixiang Eye Hosp, Dept Ophthalmol, Suzhou, Jiangsu, Peoples R China ^[2] Nantong Univ, Med Coll, Dept Pathogen Biol, Nantong, Jiangsu, Peoples R China ^[3] Shanghai Key Lab Ocular Fundus Dis, Shanghai, Peoples R China ^[4]

关键词 Diabetic retinopathy (DR)Prodrug of epigallocatechin-3-gallate (pro-EGCG)Retinal Muller cells Reactive oxygen species (ROS)Thioredoxin interacting protein (TXNIP)NACHT LRR and PYD domain-containing protein 3 (NLRP3) inflammasome Proangiogenic factor

发布时间 2021-06-18

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